Overproduction of uric acid in the body can be an indication of cell breakdown. This may be an advance indication of illness such as gout, leukemia, or lymphoma. Over a period of months, an adult male patient has taken ten blood tests for uric acid. The mean concentration was x = 5.35 mg/dl. The distribution of uric acid in healthy adult males can be assumed to be normal, with σ = 1.91 mg/dl.

 

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The small sample size of 10 suggests using a t-test with 9 degrees of freedom and a 95% 2-tailed confidence level. From t-tables we get t=2.262. We need to adjust the pop SD to 1.91/√10=0.604.

X represents a value above the mean such that (X-5.35)/0.604=2.262, X-5.35=1.37 approx. So 3.98≤X≤6.72 mg/dl. With 95% confidence the mean will be in this range.

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